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|Title:||Inhibitory activity of cyclohexenyl chalcone derivatives and flavonoids of fingerroot, Boesenbergia rotunda (L.), towards dengue-2 virus NS3 protease||Authors:||Kiat, T.S.
|Issue Date:||2006||Abstract:||Boesenbergia rotunda (L.) cyclohexenyl chalcone derivatives, 4-hydroxypanduratin A and panduratin A, showed good competitive inhibitory activities towards dengue 2 virus NS3 protease with the Ki values of 21 and 25 μM, respectively, whilst those of pinostrobin and cardamonin were observed to be non-competitive. NMR and GCMS spectroscopic data formed the basis of assignment of structures of the six compounds isolated. © 2006 Elsevier Ltd. All rights reserved.||URI:||http://dspace.uniten.edu.my/jspui/handle/123456789/9830|
|Appears in Collections:||COE Scholarly Publication|
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