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Please use this identifier to cite or link to this item: http://dspace.uniten.edu.my/jspui/handle/123456789/9830
Title: Inhibitory activity of cyclohexenyl chalcone derivatives and flavonoids of fingerroot, Boesenbergia rotunda (L.), towards dengue-2 virus NS3 protease
Authors: Kiat, T.S. 
Pippen, R. 
Yusof, R. 
Ibrahim, H. 
Khalid, N. 
Rahman, N.A. 
Issue Date: 2006
Abstract: Boesenbergia rotunda (L.) cyclohexenyl chalcone derivatives, 4-hydroxypanduratin A and panduratin A, showed good competitive inhibitory activities towards dengue 2 virus NS3 protease with the Ki values of 21 and 25 μM, respectively, whilst those of pinostrobin and cardamonin were observed to be non-competitive. NMR and GCMS spectroscopic data formed the basis of assignment of structures of the six compounds isolated. © 2006 Elsevier Ltd. All rights reserved.
URI: http://dspace.uniten.edu.my/jspui/handle/123456789/9830
Appears in Collections:COE Scholarly Publication

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