Compatibility studies of dimethyl(phenyl)silyl group as a masked hydroxyl group in compounds containing cyclopropane rings and in compounds containing the enone functionality

Abstract

Compatibility of the phenyl(dimethyl)silyl group as a masked hydroxyl group in the presence of cyclopropane rings and the enone functionality was studied. The result showed that conditions for the silyl-to-hydroxyl group conversion is not compatible with cyclopropane rings. However, under a modified two-step transformation procedure, the silyl group is converted to a hydroxyl group in the presence of an enone group without disturbing the carbon-carbon double bond, to a certain extent. © 1993, Taylor & Francis Group, LLC. All rights reserved.